Protein Details: Aquaporin AQPAe.a

Protein ID

ICDB_Pro_1577

Protein Name

Aquaporin AQPAe.a

Gene Name

AAEL003512

Organism

Aedes aegypti (Yellowfever mosquito) (Culex aegypti)

Length

249 amino acids

AlphaFoldDB

AF-Q9NHW7-F1-model_v4.pdb

Function

Forms a water-specific channel.

Sequence

MTESAGVKQLVGVADITENRNIWRMLVAEFLGTFFLVSIGIGSTMGWGGDYAPTMTQIAFTFGLVVATLAQAFGHVSGCHINPAVTIGLMITADISILKGAFYIVSQCVGAIAGAALIKAATPSDVIGGLGVTGIDPRLTAGQGVMIEALITFILVFVVHGVCDNRRSDIKGSAPLAIGLSITAGHLSAIKYTGASMNPARSFGPAVVMGNWTDQWVYWVGPIVGGILAGAVYRLFFKVRKGDEESYDF

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Localized in tracheolar cells associated with the Malpighian tubules.

DOI ID

10.1046/j.1365-2583.2000.00201.x; 10.1126/science.1138878

RefSeq

XP_001656931.1